期刊信息
![](/web/statics/zr_qikan_img.jpg)
- 刊名: 河北师范大学学报(自然科学版)Journal of Hebei Normal University (Natural Science)
- 主办: 河北师范大学
- ISSN: 1000-5854
- CN: 13-1061/N
- 中国科技核心期刊
- 中国期刊方阵入选期刊
- 中国高校优秀科技期刊
- 华北优秀期刊
- 河北省优秀科技期刊
Ligand-exchange Chromatography Stationary Phase for Chiral Resolution in High Performance Liquid
摘要/Abstract
摘要:
综述了高效液相色谱配体交换色谱手性固定相的发展、制备及其在手性拆分中的应用,讨论了洗速、进样量、中心金属离子及其浓度、流动相pH值、柱温、有机改性剂等对对映体分离的影响,阐述了对手性识别机理的认识.
Abstract:
Developments of liquid chromatographic ligand exchange chiral stationary phases for the direct separation enantiomers in high performance liquid chromatography are reviewed.Factors affecting enantiomeric resolution including flow-rate,sample size,metal ions,concentration of metal/complex,eluent pH,column temperature,organic modifier are discussed.The views on the chiral recognition mechanism are also introduced.