期刊信息

  • 刊名: 河北师范大学学报(自然科学版)Journal of Hebei Normal University (Natural Science)
  • 主办: 河北师范大学
  • ISSN: 1000-5854
  • CN: 13-1061/N
  • 中国科技核心期刊
  • 中国期刊方阵入选期刊
  • 中国高校优秀科技期刊
  • 华北优秀期刊
  • 河北省优秀科技期刊

庆大霉素发酵液的超滤过程研究

  • 1. 邯郸学院化学系, 河北邯郸 056005;
    2. 邯郸市第二制药厂技术科, 河北邯郸 056004
  • DOI:

Study on Ultrafiltrate Process of Gentamicin Fermentation Broth

摘要/Abstract

摘要:

研究了庆大霉素发酵液的超滤过程.截留分子量30 000、压强0.2 MPa、室温和酸性条件下超滤膜可去除97.85%蛋白质、60.89%COD和99.95%菌体.发酵液稀释0.1倍,可提高79.61%的超滤处理量.通过清洗后水通量可恢复94.93%.超滤可延长阴离子树脂的使用寿命,降低活性炭、阳离子树脂的消耗,节约工业用水.

Abstract:

The ultraf iltrate process of gentamicin fermentation broth was introduced.The ultraf iltrate cond-ition was: Polysulfone(PS) membrane of 30 000 molecular weight cut of (MWCO),operating pressure 0.2MPa,customary temperature and pH,97.85 % proteins,60.89% COD and 99.95% thalli were wiped of f.The fractional yield of membrane was increased of 79.61% when the fermentation broth was dilute with 0.1 times vo-lume of w ater.The recovery of membrane w ater flux could reach up to 94.93% after cleaning.Ultrafilt rate process could prolong longevity of cation resin,reduce dosages of active carbon and anionic resin,and economize water in industry.