期刊信息
- 刊名： 河北师范大学学报（自然科学版）Journal of Hebei Normal University (Natural Science)
- 主办： 河北师范大学
- ISSN： 1000-5854
- CN： 13-1061/N
- 中国科技核心期刊
- 中国期刊方阵入选期刊
- 中国高校优秀科技期刊
- 华北优秀期刊
- 河北省优秀科技期刊
正常血浆与正常全血在凝血过程中物理性能的差异
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1. 廊坊师范学院物理与电子信息学院, 河北廊坊 065000;
2. 华北煤炭医学院秦皇岛分院, 河北秦皇岛 066001;
3. 中国中医科学院, 北京 100700； -
DOI：
Dif ferences of Physical Properties in the Course of Coagulation between Normal Plasma and Normal Whole Blood
摘要/Abstract
针对用旋转粘度计在恒定低切变率下测定抗凝血样复钙后的切应力随时间而变化的曲线,研究凝血状态检测和抗凝血药物的方法,提出了一种血液流变学理论模型,把血样看作非线性Maxwell流体,其物理性能(弹性模量和粘度等)都随凝血过程中结构的演化而变化.应用理论模型拟合实验结果,找出正常血浆与正常全血在低切变率下凝血过程中物理性能的差异.结果表明,正常血浆较正常全血的凝血过程慢,其粘度和屈服应力明显小,其凝固体的弹性却稍大.
Based on the curve (the shear stress versus the time) of an ant icoagulative blood sample after recalcification under a constant low shear rate in a rotat ional viscometer is proposed,a hemorheological model is proposed to analyze blood coagulaltion and ant icoagulative drugs.When the blood is considered as a nonlinear Maxwell fluid,the elast ic modulus and viscosity vary with the evolution of microstructure during blood clotting.The experiment results are fitted by using hemorheolog ical model,and the differences in parameters of the hemorheolog lcal model between normal plasma and normal whole blood are found.The results show that the coagulation speed,yieldst ress and viscosity of normal plasma are much less than those of normal whole blood.Moreover,elastic modulus of normal plasma coagulation is a little bigger than those of normal whole blood.