期刊信息

  • 刊名: 河北师范大学学报(自然科学版)Journal of Hebei Normal University (Natural Science)
  • 主办: 河北师范大学
  • ISSN: 1000-5854
  • CN: 13-1061/N
  • 中国科技核心期刊
  • 中国期刊方阵入选期刊
  • 中国高校优秀科技期刊
  • 华北优秀期刊
  • 河北省优秀科技期刊

Fe(Ⅱ)-2,2’-联吡啶分光光度法测定维生素B1

  • 河北医科大学基础医学院, 河北 石家庄 050017
  • DOI:

Spectrophotometric Determination of Vitamin B1 Using Iron( ò )-2, 2.-bipyrinine System

摘要/Abstract

摘要:

基于维生素B1(VB1)可将Fe(Ⅲ)还原为Fe(Ⅱ),生成的Fe(Ⅱ)与2,2’联吡啶形成桔红色配合物,建立了偶合反应分光光度法测定VB1的新方法.线性范围2.4~21.0mg/L,相对标准偏差为2.7%.该方法用于VB1片剂、针剂的测定,结果与药典标准方法测得值一致.

Abstract:

new method for determination VB1by Spectrophotometry was developed based on Fe( ó )as the oxidizer of vitamin B1 and 2,2.-dipyridine as the coloring reagent of Fe( ò ) which was produced from Fe( ó ).Linear range 2.4~ 21.0mg/L,the relative standard deviation is 2.7%(Q= 10.0mg/ L,n=11).T he method has been used to determine VB1 in injection and tablets with satisfactory effects.