For some time now,the study of Regional Economic Geography is hard in the conversion from the old thinking to the new ideas.Many scholars have exerted efforts to explore the structure and thinking system of the basic characteristics of Regional Economic Geography.This study proposes the research object,focus on the core issues and the performance of Regional Economic Geography."Development and operation" is the core issue of this subject and this brand-new concept is expiained and analysed;the "basic features" of Regional Economic Geography is taken into the system.It is proved that through the evaluation of the six elemen ts:regional conditions,regional development and the course of it,regional economic structure,regional differences,regional strategies and operational measures Where and how to use the six elements are interprete di Meanwhile,the article also explained the flexible applicotion of the Regional Economic Geography it's believed that China is a country with complex geography.Effective completion of the conversion of the Regional Economic Geography thinking mode,breaking the traditional description of the shackles of thinking,establishing a new system of thinking description is very significant in theory and application.