期刊信息
- 刊名： 河北师范大学学报（自然科学版）Journal of Hebei Normal University (Natural Science)
- 主办： 河北师范大学
- ISSN： 1000-5854
- CN： 13-1061/N
- 中国科技核心期刊
- 中国期刊方阵入选期刊
- 中国高校优秀科技期刊
- 华北优秀期刊
- 河北省优秀科技期刊
MRP1/CD9与肺癌的关系
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1. 唐山职业技术学院基础医学部, 河北唐山063004;
2. 唐山市肿瘤医院放化科, 河北唐山063001;
3. 河北师范大学生命科学学院, 河北石家庄050016;
4. 华北煤炭医学院生理教研室, 河北唐山063000 -
DOI：
The Relationship Between MRP1/CD9 and Lung Carcinoma
摘要/Abstract
肺癌发病率和死亡率增长较快,对人类健康和生命有很大威胁,早期发现早期治疗是诊治关键.MRP1/CD9是跨膜蛋白,属于TM4SF家族,与肿瘤恶性程度高低和转移有密切关系.检测肺癌组织中MRP1/CD9的表达水平有助于监测病情的进展、评估治疗效果、判定预后,为早期发现早期治疗提供指导意义.综述了MRP1/CD9的结构、功能、作用机制及与肺癌的关系的研究进展.
The rapidly increasing incidence and mortality rate of lung carcinoma are threatening human.shealth and life.Early diagnosis and treatment are key to the curative effect.MRP1/CD9,which is a transmembrane,is af filiated to TM4SF family,closely correlated to malignant degree and metastasis of neoplasm.The expression of MRP1/CD9 in lung carcinoma will help to detect the development of carcinoma,evaluate the therapeutic effect,predict prognosis,diagnosis and treat early.The structure and function of MRP1/CD9 are reviewed,and it sresearch advance and its relationship with lung carcinoma are illusteated.