河北师范大学学报—

期刊信息

刊名：河北师范大学学报（自然科学版）Journal of Hebei Normal University (Natural Science)
主办：河北师范大学
ISSN： 1000-5854
CN： 13-1061/N
中国科技核心期刊
中国期刊方阵入选期刊
中国高校优秀科技期刊
华北优秀期刊
河北省优秀科技期刊

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友情链接

老年缺血性心肌病患者多模态超声和hs-CRP检测对心肌缺血的诊断效能及严重程度评估价值

沈健¹

王丽莉²

孙启玉³

张皓然⁴

李莎⁵

(1.承德医学院附属医院神经功能检查室，河北承德 067000； 2.承德市中心医院神经诊断科，河北承德 067000； 3.承德医学院附属医院南区检验科，河北承德 067000； 4.承德医学院附属医院心脏内科，河北承德 067000； 5.承德医学院附属医院超声科，河北承德 067000)
DOI： 10.13763/j.cnki.jhebnu.nse.202604013

Diagnostic efficacy and severity evaluation value of multimodal ultrasound and hs-CRP detection for myocardial ischemia in elderly patients with ischemic cardiomyopathy

Shen Jian¹,Wang Lili²,Sun Qiyu³,Zhang Haoran⁴,Li Sha⁵

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摘要/Abstract

摘要：

本研究探讨了多模态超声参数、臂踝脉搏波传导速度（brachial-ankle pulse wave velocity,baPWV）、血清高敏C反应蛋白（high-sensitivity C-reactive protein,hs-CRP）水平对老年缺血性心肌病患者心肌缺血的诊断价值及病情评估的意义.选取186例患者与60例健康对照者，均接受多模态超声（检测颅内动脉及颈动脉内中膜厚度）、baPWV和hs-CRP检测.根据Gensini评分将患者分为低、中、高危组.结果显示，Gensini评分与baPWV、hs-CRP以及多模态超声参数呈正相关.单因素及多元分析表明，baPWV、hs-CRP及多模态超声指标是影响病情的独立因素.ROC分析显示，各项指标单独诊断效能良好，联合检测（baPWV+hs-CRP+多模态超声）诊断价值最高（AUC=0.994）.老年缺血性心肌病患者的baPWV、hs-CRP及多模态超声参数与病情严重程度正相关，联合检测有更优越的诊断效能，值得临床推广应用.

Abstract：

This study explores the value of multimodal ultrasound parameters,brachial-ankle pulse wave velocity(baPWV),and serum high-sensitivity C-reactive protein(hs-CRP) levels in diagnosing myocardial ischemia and assessing disease severity in elderly patients with ischemic cardiomyopathy.A total of 186 patients and 60 healthy controls were selected,all of whom underwent multimodal ultrasound(detecting intracranial arteries and carotid intima-media thickness),baPWV,and hs-CRP testing.Patients were divided into low-,medium-,and high-risk groups based on Gensini scores.Results indicated that Gensini scores were positively correlated with baPWV,hs-CRP,and multimodal ultrasound parameters.Univariate and multivariate analyses showed that baPWV,hs-CRP,and multimodal ultrasound indicators were independent factors influencing disease severity.ROC curve analysis revealed that each individual indicator had good diagnostic performance,while combined detection(baPWV+hs-CRP+multimodal ultrasound) demonstrated the highest diagnostic efficacy(AUC=0.994).In elderly patients with ischemic cardiomyopathy,baPWV,hs-CRP,and multimodal ultrasound parameters are positively correlated with disease severity,and combined detection offers superior diagnostic performance,making it suitable for clinical application.

关键词

关键词： 缺血性心肌病；病变严重程度；多模态超声；臂踝脉搏波传导速度；高敏C反应蛋白

Key words： ischemic cardiomyopathy ; severity of the lesion ; multimodal ultrasound ; brachial-ankle pulse wave velocity ; high-sensitivity C-reactive protein

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