期刊信息

  • 刊名： 河北师范大学学报（自然科学版）Journal of Hebei Normal University (Natural Science)
  • 主办： 河北师范大学
  • ISSN： 1000-5854
  • CN： 13-1061/N
  • 中国科技核心期刊
  • 中国期刊方阵入选期刊
  • 中国高校优秀科技期刊
  • 华北优秀期刊
  • 河北省优秀科技期刊

协同采编系统

友情链接

屏状核的解剖结构及生理功能

  • （河北师范大学 生命科学学院,河北石家庄 050024）
  • DOI： 10.13763/j.cnki.jhebnu.nse.202304001

Anatomical Structure and Physiological Function of Claustrum

摘要/Abstract

摘要：

屏状核位于大脑外囊和极外囊之间,是一层很薄的灰质,由于其特殊的位置以及与大脑皮层的很多区域存在着双向连接,被认为是大脑的“意识开关”. 一直以来,我们对屏状核的功能知之甚少,促使研究者们努力揭开其神秘面纱. 综述了屏状核在组织结构、纤维联系的特点和屏状核对意识产生、认知功能、睡眠等调节机制的最新进展,以期为进一步深入认识屏状核的结构及生理作用提供参考.

Abstract：

The claustrum is a thin layer of gray matter located between the cerebral external capsule and extreme capsule. Because of its special location and bidirectional connections with many areas of the cerebral cortex,it is considered to be the brain′s “conscious switch”. Until recently,little was known about the function of claustrum. Herein,the latest progress in the organization of claustrum,the characteristics of fiber connections,as well as the regulation mechanism of claustrum on consciousness,cognitive function and sleep has been reviewed,in order to provide a reference for further understanding of the structure and physiological role of claustrum.

关键词

关键词： 屏状核 ; 大脑皮层 ; 意识 ; 认知 ; 睡眠
Key words： claustrum ; cerebral cortex ; consciousness ; cognition ; sleep

参考文献 49

  • [1] CRICK F C,KOCH C.What is the Function of the Claustrum? [J]. Philosophical Transactions Biological Sciences,2005,360(1458):1271-1279. doi: 10.1098/rstb.2005.1661
  • [2] KOWIAN＇SKI P,DZIEWIATKOWSKI J,KOWIAN＇SKA J,et al.Comparative Anatomy of the Claustrum in Selected Species:A Morphometric Analysis [J]. Brain Behav Evol,1999,53(1):44-54. doi: 10.1159/000006581
  • [3] BRAND S.A Serial Section Golgi Analysis of the Primate Claustrum [J]. Anat Embryol (Berl),1981,162(4):475-488. doi: 10.1007/bf00301872
  • [4] SMITH J B,ALLOWAY K D,HOF P R,et al.The Relationship Between the Claustrum and Endopiriform Nucleus:A Perspective Towards Consensus on Cross-species Homology [J]. J Comp Neurol,2019,527(2):476-499. doi: 10.1002/cne.24537
  • [5] JACKSON J,SMITH J B,LEE A K.The Anatomy and Physiology of Claustrum-cortex Interactions [J]. Annu Rev Neurosci,2020,43:231-247. doi: 10.1146/annurev-neuro-092519-101637
  • [6] SMITH J B,LEE A K,JACKSON J.The Claustrum [J]. Curr Biol,2020,30(23):R1401-R1406. doi: 10.1016/j.cub.2020.09.069
  • [7] FANG C,WANG H,NAUMANN R K.Developmental Patterning and Neurogenetic Gradients of Nurr1 Positive Neurons in the Rat Claustrum and Lateral Cortex [J]. Front Neuroanat,2021,15:786329. doi: 10.3389/fnana.2021.786329
  • [8] GOLL Y,ATLAN G,CITRI A.Attention:The Claustrum [J]. Trends in Neurosciences,2015,38(8):486-95. doi: 10.1016/j.tins.2015.05.006
  • [9] MATHUR B N.The Claustrum in Review [J]. Frontiers in Systems Neuroscience,2014,8:48. doi: 10.3389/fnsys.2014.00048
  • [10] ZINGG B,DONG H W,TAO H W,et al.Input-output Organization of the Mouse Claustrum [J]. Journal of Comparative Neurology,2018,526(15):2428-2443. doi: 10.1002/cne.24502
  • [11] WANG Q,NG L,HARRIS J A,et al.Organization of the Connections Between Claustrum and Cortex in the Mouse [J]. Journal of Comparative Neurology,2017,525(6):1317-1346. doi: 10.1002/cne.24047
  • [12] SMITH J B,ALLOWAY K D.Interhemispheric Claustral Circuits Coordinate Sensory and Motor Cortical Areas That Regulate Exploratory Behaviors [J]. Frontiers in Systems Neuroscience,2014,8:93. doi: 10.3389/fnsys.2014.00093
  • [13] JACKSON J,KARNANI M M,ZEMELMAN B V,et al.Inhibitory Control of Prefrontal Cortex by the Claustrum [J]. Neuron,2018,99(5):1029-1039.e4. doi: 10.1016/j.neuron
  • [14] SMITH J B,LIANG Z,WATSON G D R,et al.Interhemispheric Resting-state Functional Connectivity of the Claustrum in the Awake and Anesthetized States [J]. Brain Structure & Function,2017,222(5):2041-2058. doi: 10.1007/s00429-016-1323-9
  • [15] SMITH J B,WATSON G D R,LIANG Z,et al.A Role for the Claustrum in Salience Processing? [J] Frontiers In Neuroanatomy,2019,13:64. doi: 10.3389/fnana.2019.00064
  • [16] SEARLE J R.Mind: A Brief Introduction (Fundamentals of Philosophy) [M]. New York: Oxford University Press,2004:160-170
  • [17] LEUNG A,Cohen D,van SWINDEREN B,et al.Integrated Information Structure Collapses with Anesthetic Loss of Conscious Arousal in Drosophila Melanogaster [J]. PLoS Computational Biology,2021,17(2):e1008722. doi: 10.1371/journal.pcbi.1008722
  • [18] NARIKIYO K,MIZUGUCHI R,MITSUI S,et al.The Claustrum Coordinates Cortical Slow-wave Activity [J]. Nature Neuroscience,2020,23(6):741-753. doi: 10.1038/s41593-020-0625-7
  • [19] CHAU A,SALAZAR A M,KRUEGER F,et al.The Effect of Claustrum Lesions on Human Consciousness and Recovery of Function [J]. Consciousness & Cognition,2015,36:256-264. doi: 10.1016/j.concog.2015.06.017
  • [20] WONG K,NAIR A,AUGUSTINE G J.Changing the Cortical Conductor′s Tempo: Neuromodulation of the Claustrum [J]. Frontiers in Neural Circuits,2021,15:658228. doi: 10.3389/fncir.2021.658228
  • [21] KOUBEISSI M Z,BARTOLOMEI F,BELTAGY A,et al.Electrical Stimulation of a Small Brain Area Reversibly Disrupts Consciousness [J]. Epilepsy & Behavior,2014,37:32-35. doi: 10.1016/j.yebeh.2014.05.027
  • [22] SALAZAR A M,GRAFMAN J H,VANCE S C,et al.Consciousness and Amnesia After Penetrating Head Injury:Neurology and Anatomy [J]. Neurology,1986,36(2):178. doi: 10.1212/wnl.36.2.178
  • [23] SNIDER S B,HSU J,DARBY R,et al.Cortical Lesions Causing Loss of Consciousness Are Anticorrelated with the Dorsal Brainstem [J]. Human Brain Mapping,2020,41(6):1520-1531. doi: 10.1002/hbm.24892
  • [24] HORN J.What Is Old Is New Again: Investigating and Analyzing the Mysteries of the Claustrum [J]. Neuroinformatics,2019,17(1):1-3. doi: 10.1007/s12021-018-9411-z
  • [25] LIU J,WU R,JOHNSON B,et al.The Claustrum-prefrontal Cortex Pathway Regulates Impulsive-like Behavior [J]. Journal of Neuroscience,2019,39(50):10071-10080. doi:10.1523/jneurosci.1005-19.2019
  • [26] WHITE M G,CODY P A,BUBSER M,et al.Cortical Hierarchy Governs Rat Claustrocortical Circuit Organization [J]. Journal of Comparative Neurology,2017,525(6):1347-1362. doi: 10.1002/cne.23970
  • [27] ALLOWAY J.Functional Specificity of Claustrum Connections in the Rat: Interhemispheric Communication Between Specific Parts of Motor Cortex [J]. Journal of Neuroscience,2010,30(50):16832-16844. doi: 10.1523/jneurosci.4438-10.2010
  • [28] WHITE M G,PANICKER M,MU C,et al.Anterior Cingulate Cortex Input to the Claustrum Is Required for Top-down Action Control [J]. Cell Reports,2018,22(1):84-95. doi: 10.1016/j.celrep.2017.12.023
  • [29] JACKSON J,KARNANI M M,ZEMELMAN B V,et al.Inhibitory Control of Prefrontal Cortex by the Claustrum [J]. Neuron,2018,99(5):1029-1039.e4. doi: 10.1016/j.neuron.2018.07.031
  • [30] MCGARRY L M,CARTER A G.Inhibitory Gating of Basolateral Amygdala Inputs to the Prefrontal Cortex [J]. Journal of Neuroscience,2016,36(36):9391-406. doi: 10.1523/jneurosci.0874-16
  • [31] KRIMMEL S R,QADUR H,HESSELGRAVE N,et al.Resting State Functional Connectivity of the Rat Claustrum [J]. Frontiers In Neuroanatomy,2019,13:22. doi: 10.3389/fnana.2019.00022
  • [32] WANG Q,HARRIS J A,FENG D,et al.Organization of the Connections Between Claustrum and Cortex in the Mouse [J]. Journal of Comparative Neurology,2017,525(6):1317-1346. doi: 10.1002/cne.24047
  • [33] NORIMOTO H,FENK L A,Li H H,et al.A Claustrum in Reptiles and Its Role in Slow-wave Sleep [J]. Nature,2020,578(7795):413-418. doi: 10.1038/s41586-020-1993-6
  • [34] WEBER F,DAN Y.Circuit-based Interrogation of Sleep Control [J]. Nature,2016,538(7623):51-59. doi: 10.1038/nature19773
  • [35] SHEIN-IDELSON M,ONDRACEK J M,LIAW H P,et al.Slow Waves,Sharp Waves,Ripples,and REM in Sleeping Dragons [J]. Science,2016,352(6285):590. doi: 10.1126/science.aaf3621
  • [36] RENOUARD L,BILLWILLER F,OGAWA K,et al.The Supramammillary Nucleus and the Claustrum Activate the Cortex During REM Sleep [J]. Science Advances,2015,1(3):e1400177. doi: 10.1126/sciadv.1400177
  • [37] HONG C C.fMRI Evidence for Multisensory Recruitment Associated with Rapid Eye Movements During Sleep [J]. Human Brain Mapping,2009,30(5):1705-1722. doi: 10.1002/hbm.20635
  • [38] ARNOW B A,DESMOND J E,BANNER L L,et al.Brain Activation and Sexual Arousal in Healthy,Heterosexual Males [J]. Brain,2002,125(5):1014-1023. doi: 10.1093/brain/awf108
  • [39] REDOUTE J,STOLERU S,PUGEAT M,et al.Brain Processing of Visual Sexual Stimuli in Treated and Untreated Hypogonadal Patients [J]. Psychoneuroendocrinology,2005,30(5):461-482. doi: 10.1016/j.psyneuen.2004.12.003
  • [40] 甘子明,刘纯红.大鼠屏状核中雌、雄激素受体表达及其生物学意义 [J]. 陕西医学杂志,2003,32(5):471-473. doi: 10.3969/j.issn.1000-7377.2003.05.047 GAN Ziming,LJU Chunhong.Expression and Biological Significance of Estrogen and Androgen Receptors in Rat Screen-shaped Nucleus [J]. Shaanxi Medical Journal.2003,32(5):471-473.
  • [41] 阿地力江·伊明,甘子明,薛志琴,等.大鼠屏状核神经元中雄激素与雌激素受体的表达 [J]. 新疆医科大学学报,2005,28(4):326-328. doi: 10.3969/j.issn.1009-5551.2005.04.013 ADIJIANG·Yiming,GAN Ziming,XU Zhiqin,et al.Expression of Androgen and Estrogen Receptors in the Rat Claustrum [J]. Journal of Xinjiang Medical University.2005,28(4):326-328.
  • [42] BENNETT C M,BAIRD A A.Anatomical Changes in the Emerging Adult Brain: A Voxel-based Morphometry Study [J]. Human Brain Mapping,2006,27(9):766-777. doi: 10.1002/hbm.20218
  • [43] BARON-COHEN S,RING H A,WHEELWRIGHT S,et al.Social Intelligence in the Normal and Autistic Brain: An Fmri Study [J]. European Journal of Neuroscience,1999,11(6):1891-1898. doi: 10.1046/j.1460-9568.1999.00621.x
  • [44] MARCEL ADAM J,CHERKASSKY V L,KELLER T A,et al.Functional and Anatomical Cortical Underconnectivity in Autism: Evidence from an Fmri Study of an Executive Function Task and Corpus Callosum Morphometry [J]. Cerebral Cortex,2007,17(4):951-961. doi: 10.1093/cercor/bhl006
  • [45] FERNANDEZ-MIRANDA J C,RHOTON A L,YUKINARI K,et al.The Claustrum and Its Projection System in the Human Brain: A Microsurgical and Tractographic Anatomical Study [J]. Journal of Neurosurgery,2008,108(4):764-774. doi: 10.3171/jns/2008/108/4/0764
  • [46] BRADLEY E A,ISAACS B J.Inattention,Hyperactivity,and Impulsivity in Teenagers with Intellectual Disabilities,with and Without Autism [J]. The Canadian Journal of Psychiatry,2006,51(9):598-606. doi: 10.1192/bjp.189.2.200
  • [47] HERBERT M,ZIEGLER D,DEUTSCH C,et al.Dissociations of Cerebral Cortex,Subcortical and Cerebral White Matter Volumes in Autistic Boys [J]. Brain,2003,126(5):1182-1192. doi: 10.1093/brain/awg110
  • [48] DAVIS W B.The Claustrum in Autism and Typically Developing Male Children: A Quantitative Mri Study [D]. Provo: Brigham Young University,2008.
  • [49] NIU M,KASAI A,TANUMA M,et al.Claustrum Mediates Bidirectional and Reversible Control of Stress-induced Anxiety Responses [J]. Science Advances,2022,8(11):eabi6375. doi: 10.1126/sciadv.abi6375

版权所有 2013-2021 河北师范大学学报编辑部 地址：河北省石家庄市南二环东路20号

邮编：050024 电话：0311-80786360 技术支持：载驰科技