The Belt and Road Initiative will provide historic opportunities for international cooperation and development for countries along the routes, but the lack of globally competitive talents has become the bottleneck for Chinese enterprises to "go global." Therefore, we should strengthen the cultivation of globally competitive talents, optimize the composition of trained personnel, and balance the distribution of talents in different regions. In particular, we should cultivate high-end interdisciplinary globally competitive talent that are in short supply. We should give full play to the advantages of the integrated resource of government, competitive advantage of enterprises in markets, intellectual advantage of colleges and universities, scientific research advantage of think tanks, and integration of politics, industry, learning and research, so as to cultivate globally competitive talents, thus provide personnel guarantee for the Belt and Road Initiative.