在线阅读 --自然科学版 2009年1期《1, 5-苯并硫氮杂-α-顺丁烯二酰亚氨基-β-内酰胺的合成与晶体结构》
1, 5-苯并硫氮杂-α-顺丁烯二酰亚氨基-β-内酰胺的合成与晶体结构--[在线阅读]
杜彩云1, 杨贵亭2, 蔡冬梅1, 王喜平3
1. 河北工程大学理学院, 河北邯郸 056038;
2. 邯郸学院化学系, 河北邯郸 056005;
3. 石家庄市第25中学, 河北石家庄 050021
起止页码: 70--73页
DOI:
摘要
合成了1,5-苯并硫氮杂-α-顺丁烯二酰亚氨基-β-内酰胺.结构经IR和X射线衍射分析方法得以确证.目标产物的收率为37%,该化合物的晶体属单斜晶系.晶体结构测定结果表明,化合物分子中的七员环为类椅式构象,顺丁烯二酰亚氨基和苯基位于β-内酰胺环的一侧.

Synthesis and Crystal Structure ofα-maleimidyl-β-lactam of 1,5-benzothiazepine
DU Cai-yun1, YANG Gui-ting2, CAI Dong-mei1, WANG Xi-ping3
1. College of Science, Hebei University of Engineering, Hebei Handan 056038, China;
2. Department of Chemistry, Handan College, Hebei Handan 056005, China;
3. Shijiazhuang No.25 Middle School, Hebei Shijiazhuang 050021, China
Abstract:
α-maleimidyl-β-lactam of 1,5-benzot hiazepine was synt hesized.Its composition and structure were determined by IR and single-crystal X-ray diffraction.The yield of the product was 37%.The crystal belonged to monoclinic.The crystal measurement showed that the conformation of the seven-membered ring in the title molecule was that of a chair,the maleimidyl and 4-phenyl groups attached to theβ-lactam ring were in cis positions.

收稿日期: 2008-4-3
基金项目:

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